Do you ever wonder how your physician chooses an appropriate medication for you? Do you feel overwhelmed through sheer number of accessible medications? These tips will help comprehend the choices that are available. In subsequent articles, there will become more information about each class of substance. healthjade.com
While there are hundreds of medications and combinations of medications available, there are seven different classes of medication. Each class works in another way to. Your physician uses his knowledge about you as well once your specific type of diabetes to first decide if you need any medication, and if so, which class to use. He then chooses a medication from that sort. If you require medication from more than one class he might want to prescribe more than a single medication or a mix pill which has two or more medications contained in the gift basket. This article will can be a brief overview of this classes of medications and how they work.
1.) The oldest class of prescription medication is the sulfonylureas. Prior to the mid-1990s, this was the only class of oral medications available. Your body must be place produce insulin in order for these to get beneficial, as they work by stimulating the beta cells of the pancreas to secrete insulin. Some examples of the first generation of these medications are: Tolbutamide (orinase), Tolinase (tolazamide), and Diabinese (chlorpropamide). Some of the second generation medications are: Glipizide (glucatrol), extended release Glipizide (glucatrol XL), Glyburide (Micronase, Diabeta), Glynase (micronized glyburide), and Glimepiride. These medications are distinguished by how long they last as body, and if they are cleared by the kidney or the liver. There are two other drugs in this class: Prandin and Starlix, which can use before meals as they definitely last for the most short time.
2.) The biguanide class has a single medication, called Metformin. Other names are Fortamet, Glucophage, Gluymetza, and Riomet. Prescription drugs works by decreasing glucose production typically the liver, and additionally, it causes a small increase in glucose uptake by skeletal muscle. If there are no contraindications, the American Diabetes Association and also the American college of clinical endocrinologists recommends using this medication first.
3.) In the mid-1990s, the Thiazolidinedione class of medications (also known as glitizones or TZDs) was developed. Their primary mechanism of action is maximize insulin sensitivity, which leads to more glucose being taken up by skeletal muscle. Three medications were developed. The first, Rezulin (troglitazone), was taken from the market given that it was suggested to cause liver problems. The second, Avandia (rosiglitazone), was withdrawn by the market in Europe but was allowed under selling restrictions in the US because of an increase in cardiovascular events. The third medication, Actos (pioglitazone) had sales suspended in France and Germany because a report suggested it could raise the risk of bladder cancer.
4.) Drugs affecting the incretin system are divided into two subclasses:
a. The first division is formulated from injectable drugs which mimic the effect of natural incretins produced by you have to. Medications in this class include Byetta (exenetide), Bydureon (long acting exenatide) Victoza (liraglutide), and Symlin. They work by increasing insulin secretion in give an account to glucose (sugar), decreasing the rate at the fact that liver puts out glucose, decreasing appetite, and by slowing the rate the stomach empties. These medications have become quite popular this is because can help with weight loss, to get an extremely low incidence of hypoglycemia. However, these medications have been in the news because they in order to associated with pancreatitis, and may caused a slight increase in medullary thyroid cancer.
b. The medications in this class work by blocking the enzyme which breaks down the incretins. While regarding natural incretins increases somewhat, these medicine is not as effective as the injectable ones. Medications in this class include Januvia (sitagliptin), Onglyza (saxagliptin), and Tradjenta. Might being observed to watch out for complications similar on the injectable medications. They very rarely cause hypoglycemia and don’t cause weight win. They are all being evaluated to order potential cancer jeopardy.
5.) There are three Alpha Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset), and Voglibose. These work by preventing digestion of carbohydrates the actual intestine. By preventing carbohydrates from being converted into simple sugars and made available to the blood stream from the intestine, this class of medications can helps keep the blood sugar from rising after meals.
6.) The newest class of medications is the SGLT2 inhibitors, which block absorption of glucose by the kidney. By increasing the amount of glucose lost through the urine, and decreasing the amount of sugar absorbed back in the blood stream, ranges may be minimal. Because none of these medications is approved by the FDA, the names of the medications are omitted designed by this article.
7.) Insulin can be used for people with type I Diabetes and is often needed for those with type 2 High blood pressure. There are many types and delivery systems which seem discussed subsequently.
With a thorough understanding of your type of diabetes, your physician can wade through all of the options to decide on the best match a person personally. More detailed information about each drug class will be provided in subsequent articles here, and on my website, diabeticsurvivalkit.com. Feedback visit at after for information about medications, cooking videos featuring diabetic meal and dessert recipes, and current news articles.